Conversion of Organosolv and Kraft lignins into value-added compounds assisted by an acidic deep eutectic solvent

Filipe H. B. Sosa, Ana Bjelić, João A. P. Coutinho, Mariana C. Costa, Blaž Likozar, Edita Jasiukaitytė-Grojzdek, Miha Grilc and André M. da Costa Lopes

Sustainable Energy & Fuels (2022) . DOI: 10.1039/D2SE00859A
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Book Chapter: Deep Eutectic Solvents vs. ionic liquids: Similarities and differences

Filipe H. B. Sosa, João A. P. Coutinho and André M. da Costa Lopes

Current Developments in Biotechnology and Bioengineering: Deep Eutectic Solvents: Fundamentals and Emerging Applications (2022) . DOI: 10.1016/B978-0-323-99905-2.00007-8
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Assessing the hydrotropic effect in the presence of electrolytes: competition between solute salting-out and salt-induced hydrotrope aggregation

Afonso Cerqueira Martins, Jordana Benfica, Germán Peréz-Sanchéz, Seishi Shimizu, Tânia E. Sintra, Nicolas Schaeffer and João A. P. Coutinho

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Physical Chemistry Chemical Physics (2022) . DOI: 10.1039/D2CP00749E
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Sustainable extraction of antioxidants from out-of-caliber kiwifruits

Jean-Baptiste Chagnoleau, Ana M. Ferreira, Joao A.P. Coutinho, Xavier Fernandez, Stéphane Azoulay, Nicolas Papaiconomou

Food Chemistry (2022) 133992. DOI: 10.1016/j.foodchem.2022.133992
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Sustainable Development Of Biomaterials Using Ionic Liquids

Cariny Polesca, Helena Passos, João A.P. Coutinho, Mara G. Freire

Current Opinion in Green and Sustainable Chemistry (2022) 100675. DOI: 10.1016/j.cogsc.2022.100675
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Book Chapter: Biocatalysis in biphasic systems based on ionic liquids

Inês O. Baptista, Ana M. Ferreira, Flávia F. Magalhães, Mara G. Freire, Ana P. M. Tavares and João A. P. Coutinho

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Biocatalysis in Green Solvents (2022) . DOI: 10.1016/B978-0-323-91306-5.00018-2
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Insights into the Chloride versus Bromide Effect on the Formation of Urea-Quaternary Ammonium Eutectic Solvents

Mónia A. R. Martins, Dinis O. Abranches, Liliana P. Silva, Simão P. Pinho, and João A. P. Coutinho

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Industrial & Engineering Chemistry Research (2022) . DOI: 10.1021/acs.iecr.2c01274
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Imidazolium Chloride Ionic Liquid Mixtures as Separating Agents: Fuel Processing and Azeotrope Breaking

Sérgio M. Vilas-Boas, Mónia A. R. Martins, Fábio R. Tentor, Gabriel Teixeira, Juliana G. Sgorlon, João A. P. Coutinho, Olga Ferreira, and Simão P. Pinho

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Energy & Fuels (2022) . DOI: 10.1021/acs.energyfuels.2c01724
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Selection of Hydrotropes for Enhancing the Solubility of Artemisinin in Aqueous Solutions

Isabela Sales, Dinis. O. Abranches, Tânia E. Sintra, Silvana Mattedi, Mara G. Freire, João A. P. Coutinho and Simão P. Pinho

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Fluid Phase Equilibria (2022) 113556. DOI: 10.1016/j.fluid.2022.113556
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Chemical characterization of asphaltenes deposits from Hassi Messaoud field

Dounya Behnous, Youcef Bouhadda, Brian Moffatt, Nouredine Zeraibi and João A. P. Coutinho

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Fuel 328 (2022) 125305. DOI: 10.1016/j.fuel.2022.125305
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Factors driving metal partition in ionic liquid-based acidic aqueous biphasic systems

Ana R.F. Carreira, Helena Passos, Nicolas Schaeffer, Lenka Svecova, Nicolas Papaiconomou, Isabelle Billard and João A.P. Coutinho

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Separation and Purification Technology 299 (2022) 121720. DOI: 10.1016/j.seppur.2022.121720
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Book : Waste Valorisation Using Ionic Liquids

Francisca e Silva, Ana Sousa, Mara Freire and João Coutinho

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Green Chemistry Series - The Royal Society of Chemistry (2022) . DOI: 10.1039/9781839164682
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Towards the purification of IgY from egg yolk by centrifugal partition chromatography

Mafalda R.Almeida, FilipeFerreira, PedroDomingues, JoãoA. P. Coutinho and Mara G.Freire

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Separation and Purification Technology (2022) 121697. DOI: 10.1016/j.seppur.2022.121697
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Prediction of pH Value of Aqueous Acidic and Basic Deep Eutectic Solvent Using COSMO-RS σ Profiles’ Molecular Descriptors

Manuela Panić, Mia Radović, Marina Cvjetko Bubalo, Kristina Radošević, Marko Rogošić, João A. P. Coutinho, Ivana Radojčić Redovniković and Ana Jurinjak Tušek

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Molecules 27 (2022) 4489. DOI: 10.3390/molecules27144489
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Using COSMO-RS to Predict Hansen Solubility Parameters

José Pedro Wojeicchowski, Ana M. Ferreira, Tifany Okura, Marlus Pinheiro Rolemberg, Marcos R. Mafra and João A. P. Coutinho

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Industrial & Engineering Chemistry Research (2022) . DOI: 10.1021/acs.iecr.2c01592
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Cyanobacteria as Candidates to Support Mars Colonization: Growth and Biofertilization Potential Using Mars Regolith as a Resource

Inês P. E. Macário, Telma Veloso, Silja Frankenbach, João Serôdio, Helena Passos, Clara Sousa, Fernando J. M. Gonçalves, Sónia P. M. Ventura and Joana L. Pereira

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Frontiers in Microbiology 13 (2022) . DOI: 10.3389/fmicb.2022.840098
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Comment on “Structural Study of a Eutectic Solvent Reveals Hydrophobic Segregation and Lack of Hydrogen Bonding between the Components”

Nicolas Schaeffer, Liliana P. Silva and João A. P. Coutinho

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ACS Sustainable Chemistry & Engineering (2022) . DOI: 10.1021/acssuschemeng.2c02985
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An Overview on the Recent Advances in Alternative Solvents as Stabilizers of Proteins and Enzymes

Jéssica S. Almeida, Emanuel V. Capela, Ana M. Loureiro, Ana P. M. Tavares and Mara G. Freire

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ChemEngineering 6 (2022) 51. DOI: 10.3390/chemengineering6040051
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All-Aqueous Freeform Fabrication of Perfusable Self-Standing Soft Compartments

Raquel C. Gonçalves, Sara Vilabril, Catarina M. S. S. Neves, Mara G. Freire, João A. P. Coutinho, Mariana B. Oliveira and João F. Mano

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Advanced Materials (2022) . DOI: 10.1002/adma.202200352
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Integrated Approach to Extract and Purify Proteins from Honey by Ionic Liquid-Based Three-Phase Partitioning

Matheus M. Pereira, Sónia N. Pedro, Maria V. Quental, Aminou Mohamadou, João A. P. Coutinho and Mara G. Freire

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ACS Sustainable Chemistry & Engineering (2022) . DOI: 10.1021/acssuschemeng.2c01782
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Uncovering the Use of Fucoxanthin and Phycobiliproteins into Solid Matrices to Increase Their Emission Quantum Yield and Photostability

Lilia M. S. Dias, Gabriela Kovaleski, Lianshe Fu, Tânia R. Dias, Inês P. E. Macário, Sandra F. H. Correia, Joana L. Pereira, João A. P. Coutinho, Sónia P. M. Ventura and Rute A. S. Ferreira

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Applied Sciences 12 (2022) 5839. DOI: 10.3390/app12125839
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Extensive characterization of choline chloride and its solid–liquid equilibrium with water

Ana I. M. C. Lobo Ferreira, Sérgio M. Vilas-Boas, Rodrigo M. A. Silva, Mónia A. R. Martins, Dinis O. Abranches, Paula C. R. Soares-Santos, Filipe A. Almeida Paz, Olga Ferreira, Simão P. Pinho, Luís M. N. B. F. Santos and João A. P, Coutinho

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Physical Chemistry Chemical Physics (2022) . DOI: 10.1039/d2cp00377e
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Book Chapter - Advances achieved in solid-phase microextraction using polymeric ionic liquids

Marguerita E. Rosa, Francisca A. e Silva, João A. P. Coutinho and Mara G. Freire

Ionic Liquid-Based Technologies for Environmental Sustainability (2022) 347-381. DOI: 10.1016/B978-0-12-824545-3.00021-0
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Book Chapter- Achievements and perspectives of using deep eutectic solvents in the analytical chemistry field

Francisca A. e Silva and Mara G. Freire

Ionic Liquids in Analytical Chemistry (2022) 33-72. DOI: 10.1016/B978-0-12-823334-4.00002-3
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Electrolyte Effects on the Amino Acid Solubility in Water: Solubilities of Glycine, L‑Leucine, L‑Phenylalanine, and L‑Aspartic Acid in Salt Solutions of (Na+, K+, NH4 +)/(Cl−, NO3 −)

Mehriban Aliyeva, Paula Brandão, José R. B. Gomes, João A. P. Cotinho, Olga Ferreira and Simão P. Pinho

Industrial & Engineering Chemistry Research 61 (2022) 5620-5631. DOI: 10.1021/acs.iecr.1c04562
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Cholinium-Based Ionic Liquids as Efficient Media for Improving the Structural and Thermal Stability of Immunoglobulin G Antibodies

Diksha Dhiman, Meena Bisht, Ana P. M. Tavares, Mara G. Freire and Pannuru Venkatesu

ACS Sustainable Chemistry & Engineering 10 (2022) 5404-5420. DOI: 10.1021/acssuschemeng.1c07979
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Selective Separation of Vanillic Acid from Other Lignin-Derived Monomers Using Centrifugal Partition Chromatography: The Effect of pH

Inês L. D. Rocha, André M. da Costa Lopes, Sónia P. M. Ventura and João A. P. Coutinho

ACS Sustainable Chemistry & Engineering 10 (2022) 4913-4921. DOI: 10.1021/acssuschemeng.1c08082
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Liquefying Flavonoids with Terpenoids through Deep Eutectic Solvent Formation

Gabriel Teixeira, Dinis O. Abranches, Liliana P. Silva, Sérgio M. Vilas-Boas, Simão P. Pinho, Ana I. M. C. L. Ferreira, Luís, M. N. B. F. Santos, Olga Ferreira and João A. P. Coutinho

Molecules 27 (2022) 2649. DOI: 10.3390/molecules27092649
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Immobilization and Characterization of L-Asparaginase over Carbon Xerogels

Rita A. M. Barros, Raquel O. Cristóvão, Sónia A. C. Carabineiro, Márcia C. Neves, Mara G. Freire, Joaquim L. Faria, Valéria C. Santos-Ebinuma, Ana P. M. Tavares and Cláudia G. Silva

BioTech 11 (2022) . DOI: 10.3390/biotech11020010
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Deep Eutectic Solvent Formulations and Alginate-Based Hydrogels as a New Partnership for the Transdermal Administration of Anti-Inflammatory Drugs

Sónia N. Pedro, Maria S. M. Mendes, Bruno M. Neves, Isabel Filipa Almeida, Paulo Costa, Inês Correia-Sá, Carla Vilela, Mara G. Freire, Armando J. D. Silvestre and Carmen S. R. Freire

Pharmaceutics 14 (2022) 827. DOI: 10.3390/pharmaceutics14040827
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Deep Eutectic Solvents for Sustainable Separation Processes

Filipe H. B. Sosa, Mariana C. da Costa, Armando J. D. Silvestre, and André M. da Costa Lopes

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Book Chapter in Sustainable Separation Engineering: Materials, Techniques and Process Development 2 (2022) 1-48. DOI: 10.1002/9781119740117.ch17
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Ionogels for Biomedical Applications

Bojan Kopilovic, Francisca S. e Silva, Augusto Q. Pedro, João A. P. Coutinho and Mara G. Freire

Nanotechnology for Biomedical Applications; Materials Horizons: From Nature to Nanomaterials. (2022) 391-425. DOI: 10.1007/978-981-16-7483-9_18
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Bio-Based Solar Energy Harvesting for Onsite Mobile Optical Temperature Sensing in Smart Cities

Sandra F. H. Correia, Ana. R. N. Bastos, Margarida Martins, Inês P. E. Macário, Telma Veloso, Joana L. Pereira, João A. P. Coutinho, Sónia P. M. Ventura, Paulo S. André and Rute A.S. Ferreira

Advanced Science (2022) 2104801. DOI: 10.1002/advs.202104801
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Characterization of cholinium-carboxylate-based aqueous biphasic systems

Mafalda R. Almeida, Ana F. C. S. Rufino, Diana C. V. Belchior, Pedro J. Carvalho and Mara G. Freire

Fluid Phase Equilibria (2022) 113458. DOI: 10.1016/j.fluid.2022.113458
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Encapsulated Protic Ionic Liquids as sustainable materials for CO2 separation

Liliana P. Silva, Emanuel A. Crespo, Mónia A. R. Martins, Paula C. Barbosa, Ramesh L. Gardas, Lourdes F. Vega, João A. P. Coutinho and Pedro J. Carvalho

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Industrial & Engineering Chemistry Research (2022) . DOI: 10.1021/acs.iecr.1c04335
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Type V Deep Eutectic Solvents: Design and Applications

Dinis O. Abranches and João A.P. Coutinho

Current Opinion in Green and Sustainable Chemistry (2022) . DOI: 10.1016/j.cogsc.2022.100612
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Breaking the Structure of Liquid Hydrogenated Alcohols Using Perfluorinated tert-Butanol: A Multitechnique Approach (Infrared, Raman, and X‑ray Scattering) Analyzed by DFT and Molecular Dynamics Calculations

M. Isabel Cabaço, Marcel Besnard, Carlos Cruz, Pedro Morgado, Gonçalo M. C. Silva, Eduardo J. M. Filipe, João A. P. Coutinho and Yann Danten

The Journal of Physical Chemistry B 126 (2022) 1992-2004. DOI: 10.1021/acs.jpcb.1c10776
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High Performance of Ionic-Liquid-Based Materials to Remove Insecticides

Rafael Francisco, Catarina Almeida, Ana C. A. Sousa, Márcia C. Neves and Mara G. Freire

International Journal of Molecular Sciences 23 (2022) 2989. DOI: 10.3390/ijms23062989
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The Impact of Size and Shape in the Performance of Hydrotropes: A Case-Study of Alkanediols

Dinis O. Abranches, Bruna P. Soares, Ana M. Ferreira, Seishi Shimizu, Simão P. Pinho and João A. P. Coutinho

Physical Chemistry Chemical Physics 24 (2022) 7624-7634. DOI: 10.1039/D2CP00496H
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Purification of immunoglobulin Y from egg yolk using thermoresponsive aqueous micellar two-phase systems comprising ionic liquids

Filipa A. Vicente, Leonor S. Castro, Dibyendu Mondal, João A. P. Coutinho, Ana P. M. Tavares, Sónia P. M. Ventura and Mara G. Freire

Separation and Purification Technology 288 (2022) 120589. DOI: 10.1016/j.seppur.2022.120589
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Improved Production of 5-Hydroxymethylfurfural in Acidic Deep Eutectic Solvents Using Microwave-Assisted Reactions

Eduarda S. Morais, Mara G. Freire, Carmen S. R. Freire and Armando J. D. Silvestre

Molecular Sciences 23 (2022) 1959. DOI: 10.3390/ijms23041959
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Boosting Antibiotics Performance by New Formulations with Deep Eutectic Solvents

Sónia N. Pedro, Ana T. P. C. Gomes, Párástu Oskoei, Helena Oliveira, Adelaide Almeida, Mara G. Freire, Armando J.D. Silvestre, Carmen S. R. Freire

International Journal of Pharmaceutics (2022) 121566. DOI: 10.1016/j.ijpharm.2022.121566
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Supplementation of carotenoids from peach palm waste (Bactris gasipaes) obtained with an ionic liquid mediated process displays kidney anti-inflammatory and antioxidant outcomes

Aline B. Santamarina, Leonardo M. de Souza Mesquita, Breno P. Casagrande, Marcela N. Sertorio, Daniel Vitor de Souza, Laís V. Mennitti, Daniel A. Ribeiro, Débora Estadella, Sónia P.M. Ventura, Veridiana V. de Rosso, Luciana P. Pisani

Food Chemistry 13 (2022) 100245. DOI: 10.1016/j.fochx.2022.100245
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Aqueous Biphasic Systems Comprising Natural Organic Acid‐Derived Ionic Liquids

Maria V. Quental, Matheus M. Pereira, Francisca A. e Silva, João A. P. Coutinho and Mara G. Freire

Separations 9 (2022) 46. DOI: 10.3390/ separations9020046
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Physico-chemical characterization of aqueous solutions of superbase ionic liquids with cellulose dissolution capability

Mónia A. R. Martins, Filipe H. B.Sosa, Ilkka Kilpeläinen and João A. P. Coutinho

Fluid Phase Equilibria (2022) . DOI: 10.1016/j.fluid.2022.113414
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Comparison of two computational methods for solvent screening in countercurrent and centrifugal partition chromatography

Sérgio M. Vilas-Boas, Isabella W. Cordova, Kiki A. Kurnia, Heloísa H. S. Almeida, Priscilla S. Gaschi, João A. P. Coutinho, Simão P. Pinho, Olga Ferreira

Journal of Chromatography A 1666 (2022) 462859. DOI: 10.1016/j.chroma.2022.462859
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Lysine-PEGylated Cytochrome c with Enhanced Shelf-Life Stability

João H. P. M. Santos, Valker A. Feitosa, Giovanna P. Meneguetti, Gustavo Carretero, João A. P. Coutinho, Sónia P. M. Ventura and Carlota O. Rangel-Yagui

Biosensors 12 (2022) 94. DOI: 10.3390/bios12020094
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Enhanced Enzyme Reuse through the Bioconjugation of L-Asparaginase and Silica-Based Supported Ionic Liquid-like Phase Materials

João C. F. Nunes, Mafalda R. Almeida, Rui M. F. Bento, Matheus M. Pereira, Valéria C. Santos-Ebinuma, Márcia C. Neves, Mara G. Freire and Ana P. M. Tavares

Molecules 27 (2022) 929. DOI: 10.3390/ molecules27030929
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Separation of Albumin from Bovine Serum Applying Ionic‐Liquid‐Based Aqueous Biphasic Systems

Ana F. C. S. Rufino, Mafalda R. Almeida, Mukesh Sharma, João A. P. Coutinho and Mara G. Freire

Applied Sciences 12 (2022) 707. DOI: 10.3390/app12020707
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Efficient Extraction of the RuBisCO Enzyme from Spinach Leaves Using Aqueous Solutions of Biocompatible Ionic Liquids

Ana I. Valente, Ana M. Ferreira, Mafalda R. Almeida, Aminou Mohamadou, Mara G. Freire and Ana P. M. Tavares

Sustainable Chemistry 3 (2022) 1-18. DOI: 10.3390/suschem3010001
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Pretreatment of Plastic Waste: Removal of Colorants from HDPE Using Biosolvents

Ana M. Ferreira, Isa Sucena, Vanessa Otero, Eva Mariasole Angelin, Maria João Melo and João A. P. Coutinho

Molecules 27 (2022) 98. DOI: 10.3390/molecules27010098
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Development of Quantitative Structure-Property Relationship to Predict the Viscosity of Deep Eutectic Solvent for CO2 Capture using Molecular Descriptor

Kiki Adi Kurnia, Megawati Zunita, João A. P. Coutinho, I Gede Wenten and Djoko Santoso

Journal of Molecular Liquids 347 (2022) 118239. DOI: 10.1016/j.molliq.2021.118239
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Ionic Liquids or Eutectic Solvents? Identifying the Best Solvents for the Extraction Astaxanthin and β-carotene from Phaffia rhodozyma Yeast and Preparation of Biodegradable Films

Cassamo U. Mussagy, Valéria C. Santos-Ebinuma, Rondinelli D. Herculano, João A. P. Coutinho, Jorge F. B. Pereira and Adalberto Pessoa Jr.

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Green Chemistry 24 (2022) 118-123. DOI: 10.1039/D1GC03521E
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The Excess Volumes of Protic Ionic Liquids and its Significance to their Thermodynamic Modelling

Emanuel A. Crespo, Liliana P. Silva, Pedro J. Carvalho and João A. P. Coutinho

Fluid Phase Equilibria 552 (2022) 113277. DOI: 10.1016/j.fluid.2021.113277
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Building Better Biobetters: From Fundamentals to Industrial Application

Karin M. Torres-Obreque, Giovanna P. Meneguettia, Jorge J. Muso-Cachumba, Valker A. Feitosa, João H. P. M. Santos, Sónia P. M. Ventura and Carlota O. Rangel-Yagui

Drug Discovery Today 27 (2022) 65-81. DOI: 10.1016/j.drudis.2021.08.009
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